HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-{[4-Bromo-5-(3-chlorophenyl)furan-2-yl]carbonyl}piperazin-2-one → 4-{[5-(3-Chlorophenyl)-4-(3,5-dimethylphenyl)furan-2-yl]carbonyl}piperazin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-{[4-Bromo-5-(3-chlorophenyl)furan-2-yl]carbonyl}piperazin-2-one | HCID 58064764 | — |
| Reactant | 4-{[4-(3-Chlorophenyl)-5-(3-methylphenyl)furan-2-yl]carbonyl}piperazin-2-one | HCID 58064779 | — |
| Product | 4-{[5-(3-Chlorophenyl)-4-(3,5-dimethylphenyl)furan-2-yl]carbonyl}piperazin-2-one | HCID 46833183 | — |
Reaction Steps
The preparation of the title compound takes place in analogy to the synthesis of the compound from Example 18 starting with the compound from Example 27A. 15.0 mg (28% of theory) of the title compound are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08324268B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-a784189c24264ee3a46f809d57a91f2a |
| Source note | uspto-grants-2012_12 |