HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-{2-(3-Chloro-4-fluorophenyl)-5-[(4-oxoimidazolidin-1-yl)carbonyl]furan-3-yl}-5-fluorobenzenecarbonitrile → 3-{2-(3-Chlorophenyl)-5-[(4-oxoimidazolidin-1-yl)carbonyl]furan-3-yl}-5-fluorobenzenecarbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-{2-(3-Chloro-4-fluorophenyl)-5-[(4-oxoimidazolidin-1-yl)carbonyl]furan-3-yl}-5-fluorobenzenecarbonitrile | HCID 58064786 | — |
| Reactant | Ethyl 5-(3-chlorophenyl)-4-(3-cyano-5-fluorophenyl)furan-2-carboxylate | HCID 58064792 | — |
| Product | 3-{2-(3-Chlorophenyl)-5-[(4-oxoimidazolidin-1-yl)carbonyl]furan-3-yl}-5-fluorobenzenecarbonitrile | HCID 46833484 | — |
Reaction Steps
The preparation of the title compound takes place in analogy to the synthesis of the compound from Example 31 starting with the compound from Example 16A. 29.9 mg (49% of theory) of the title compound are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08324268B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-6a48b52fcbdf40d9b055fce716345d0b |
| Source note | uspto-grants-2012_12 |