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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2190534Generated: November 2, 2026

Chloride → HCID 59317999, compound

https://huagongshe.com/reaction/2190534

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorideHCID 312—
Reactant1-ethyl-1H-indol-5-amineHCID 18475534—
Reactant6-chloro-N-(4-iodo-3-methyl-phenyl)-nicotinamideHCID 59318138—
ProductHCID 59317999HCID 59317999—

Reaction Steps

6-Chloro-N-(1-ethyl-1H-indol-6-yl)-nicotinamide was prepared from 1-ethyl-1H-indol-5-ylamine (prepared as described in J. Med. Chem. 2007, 5509), and 6-chloronicotincyl chloride in a procedure similar to the one described in the synthesis of 6-chloro-N-(4-Iodo-3-methyl-phenyl)-nicotinamide, above. LCMS calcd for C16H14ClN3O (m/e) 299, obsd 300 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08324385B2
Source datasetuspto-grants-2012_12
ORD IDord-973ba1016a7e425e9a72b68eeadf3e2a
Source noteuspto-grants-2012_12