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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2190538Generated: October 27, 2026

3-tert-Butylaniline → 4-Bromo-N-(3-tert-butyl-phenyl)-2-fluoro-benzamide

https://huagongshe.com/reaction/2190538

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-tert-ButylanilineHCID 79334—
Reactant4-Bromo-2-fluorobenzoic acidHCID 302681—
Reactant4-Bromo-N-(3-tert-butyl-phenyl)-3-fluoro-benzamideHCID 59318165—
Product4-Bromo-N-(3-tert-butyl-phenyl)-2-fluoro-benzamideHCID 59317996—

Reaction Steps

4-Bromo-N-(3-tert-butyl-phenyl)-2-fluoro-benzamide was synthesized from 3-tert-butyl-phenylamine and 4-bromo-2-fluoro-benzoic acid in a manner similar to the one described in the synthesis of 4-bromo-N-(3-tert-butyl-phenyl)-3-fluoro-benzamide above. LCMS calcd for C17H17FNO (m/e) 349, obsd 350 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08324385B2
Source datasetuspto-grants-2012_12
ORD IDord-ab82b9b7ed66455fbdeb0423218edd67
Source noteuspto-grants-2012_12