HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(4-tert-Butyl-phenyl)-6-piperazin-1-yl-nicotinamide → N-(3-tert-Butyl-phenyl)-6-piperazin-1-yl-nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(4-tert-Butyl-phenyl)-6-piperazin-1-yl-nicotinamide | HCID 59318019 | — |
| Reactant | 4-[5-(3-Tert-butyl-phenylcarbamoyl)-pyridin-2-yl]-piperazine-1-carboxylic acid tert-butyl ester | HCID 59318107 | — |
| Product | N-(3-tert-Butyl-phenyl)-6-piperazin-1-yl-nicotinamide | HCID 59318114 | — |
Reaction Steps
N-(3-tert-Butyl-phenyl)-6-piperazin-1-yl-nicotinamide was prepared from 4-[5-(3-tert-butyl-phenylcarbamoyl)-pyridin-2-yl]-piperazine-1-carboxylic acid tert-butyl ester in a manner similar to the one described in the synthesis of N-(4-tert-butyl-phenyl)-6-piperazin-1-yl-nicotinamide above. HRMS m/z calcd for C20H26N4O [M+H]+: 339.2179. Found: 339.2180.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08324385B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-d48afe2f32d74f18b2b06a3cd186bdc4 |
| Source note | uspto-grants-2012_12 |