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HRID2190646

反应详情

EQUATION

反应方程式

HRID 2190646 的结构方程式

REACTANTS

反应物

3
结构：CC(C)(C)c1cccc(N)c1
HCID79334

3-tert-Butylaniline

C10H15N

结构：CC(C)(C)OC(=O)N1CCC(c2ccc(C(=O)O)cc2)CC1
HCID22492859

4-[1-(tert-Butoxycarbonyl)piperidin-4-yl]benzoic acid

C17H23NO4

结构：CC(C)(C)OC(=O)N1CCN(c2ccc(C(=O)Nc3cccc(C(C)(C)C)c3)cc2)CC1
HCID59318017

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)N1CCC(c2ccc(C(=O)Nc3cccc(C(C)(C)C)c3)cc2)CC1
HCID59318012

未命名化合物

PROCEDURE

实验过程

4-[4-(3-tert-Butyl-phenylcarbamoyl)-phenyl]-piperidine-1-carboxylic acid tert-butyl ester was prepared from N-Boc-4-(4-carboxyphenyl)piperidine and 3-tert-butyl aniline in a manner similar to the one described in the synthesis of 4-[4-(3-tert-butyl-phenylcarbamoyl)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester, above. The product was isolated after silica gel column purification with 10-50% Et2O in hexanes. HRMS m/z calcd for C26H35N3O3I [M+H]+: 437.2799. Found: 437.2796.

WORKUP

后处理

  1. customThe product was isolated
  2. customafter silica gel column purification with 10-50% Et2O in hexanes