HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(3-tert-Butyl-phenyl)-4-piperidin-4-yl-benzamide → HCID 178440930, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(3-tert-Butyl-phenyl)-4-piperidin-4-yl-benzamide | HCID 59317976 | — |
| Reactant | 3-(3-Hydroxy-5-isoxazolyl)propanoic acid | HCID 178525335 | — |
| Product | HCID 178440930 | HCID 178440930 | — |
Reaction Steps
N-(3-tert-Butyl-phenyl)-4-{1-[3-(3-hydroxy-isoxazol-5-yl)-propionyl]-piperidin-4-yl}-benzamide was prepared by the ECDI coupling of N-(3-tert-butyl-phenyl)-4-piperidin-4-yl-benzamide and 3-(3-hydroxy-isoxazol-5-yl)-propionic acid in a manner similar to the one described in the synthesis of 4-{4-[5-(3-tert-butyl-phenylcarbamoyl)-pyridin-2-yl]-piperazine-1-carbonyl}-cyclonexanecarboxylic acid methyl ester, above. LCMS calcd for C28H33N3O4 (m/e) 475, obsd 476 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08324385B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-9b5e118b22334767b7efa4b52123f76b |
| Source note | uspto-grants-2012_12 |