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HRID2190670

反应详情

EQUATION

反应方程式

HRID 2190670 的结构方程式

REACTANTS

反应物

3
结构：CCOC(=O)Cl
HCID10928

Ethyl chloroformate

C3H5ClO2

结构：Cc1ccc(NC(=O)c2ccc(N3CCNCC3)nc2)cc1I
HCID59318071

未命名化合物

结构：Cc1ccc(NC(=O)c2ccc(N3CCN(C(=O)CC(C)(C)C)CC3)nc2)cc1I
HCID59318175

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)N1CCN(c2ccc(C(=O)Nc3ccc(C)c(I)c3)cn2)CC1
HCID59318180

未命名化合物

PROCEDURE

实验过程

4-[5-(3-Iodo-4-methyl-phenylcarbamoyl)-pyridin-2-yl]-piperazine-1-carboxylic acid ethyl ester was synthesized from N-(3-iodo-4-methyl-phenyl)-6-piperazin-1-yl-nicotinamide and ethylchloroformate in a manner similar to the one described in the synthesis of 6-[4-(3,3-dimethyl-butyryl)-piperazin-1-yl]-N-(3-iodo-4-methyl-phenyl)-nicotinamide above. LCMS calcd for C20H23IN4O3 (m/e) 494, obsd 495 (M+H).