Sodium Hydroxide → HCID 54746571, compound

Participants

Reaction Steps

A mixture of [(4-hydroxy-7-methyl-2-oxo-2H-chromene-3-carbonyl)-amino]-acetic acid ethyl ester (106 mg, 0.347 mmol) and NaOH solution (0.70 mL, 1.38 mmol) in tetrahydrofuran (3 mL), methanol (3 mL) and water (3 mL) was stirred at rt overnight; the solvents were evaporated and the resulting residue was dissolved in water, acidified with 2 M HCl solution, the precipitates were then dried to give the desired product (80 mg). ESI (m/z): 278 (M+H)+.

Provenance & Evidence