Benzyl Bromide → 8-Benzyloxy-2,2-dimethyl-benzo[1,3]dioxin-4-one

HRID 2190931Notes

Reaction equation

[OH:1][C:2]1[C:11]2[O:10][C:9]([CH3:13])([CH3:12])[O:8][C:7](=[O:14])[C:6]=2[CH:5]=[CH:4][CH:3]=1.[CH2:15](Br)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[CH2:15]([O:1][C:2]1[C:11]2[O:10][C:9]([CH3:12])([CH3:13])[O:8][C:7](=[O:14])[C:6]=2[CH:5]=[CH:4][CH:3]=1)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

Reactant 2

HCID 7498Benzyl Bromide

HCID 225569958-hydroxy-2,2-dimethyl-4H-benzo[d][1,3]dioxin-4-one

Product 1

HCID 235905428-Benzyloxy-2,2-dimethyl-benzo[1,3]dioxin-4-one

Procedure

The title compound was prepared from 8-hydroxy-2,2-dimethyl-benzo[1,3]dioxin-4-one and benzylbromide under conditions analogous to experimental example 38-b, to give the desired product as an off-white solid. MS: (+) m/z 285.10 (M+1).

Sources & evidence

ORD record: ord-fd80f869909d45c5ae2fe0511b0da6ee
Source dataset: uspto-grants-2012_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08324405B2

Reaction notes

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