反应详情

5-(4-Fluoro-benzyloxy)-2,2-dimethyl-benzo[1,3]dioxin-4-one was prepared from 5-hydroxy-2,2-dimethyl-benzo[1,3]dioxin-4-one and 4-fluorobenzyl bromide under conditions analogous to example 46-a. Crude product was purified by silica gel chromatography (eluting with 40%-100% CH2Cl2 in hexanes) to provide the title compound. MS ESI(+) m/e: 303.06 (M+1).

1. customCrude product was purified by silica gel chromatography (eluting with 40%-100% CH2Cl2 in hexanes)