HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 131730098, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 68479046 | HCID 68479046 | — |
| Reactant | HCID 102106855 | HCID 102106855 | — |
| Product | HCID 131730098 | HCID 131730098 | — |
Reaction Steps
In analogy to the procedure described for the synthesis of 5-Chloro-2-[(3SR,4SR)-3-(3,4-difluoro-phenyl)-piperidin-4-ylmethoxy]-pyridine; hydrochloride the title compound was prepared from 445-Chloro-pyridin-2-yloxymethyl)-3-(4-methoxy-phenyl)-piperidine-1-carboxylic acid tert-butyl ester as off-white foam (1:1 mixture cis:trans). MS (m/e): 333.4 [(M+H)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08324248B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-c8950c947a68429aa9917ba0509c9c97 |
| Source note | uspto-grants-2012_12 |