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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2191126Generated: November 1, 2026

Hydrochloric Acid → HCID 131730099, compound

https://huagongshe.com/reaction/2191126

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 68475948HCID 68475948—
ReactantHCID 68479046HCID 68479046—
ProductHCID 131730099HCID 131730099—

Reaction Steps

In analogy to the procedure described for the synthesis of 5-Chloro-2-[(3SR,4SR)-3-(3,4-difluoro-phenyl)-piperidin-4-ylmethoxy]-pyridine; hydrochloride the title compound was prepared from (3SR,4 SR)-4-(5-Chloro-pyridin-2-yloxymethyl)-3-phenyl-piperidine-1-carboxylic acid tert-butyl ester as off-white foam. MS (m/e): 303.3 [(M+H)+].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08324248B2
Source datasetuspto-grants-2012_12
ORD IDord-5a753f47b9e54c47a9addf6f1dd50d79
Source noteuspto-grants-2012_12