HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 58241680, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | 1,3-difluoro-2-iodo-4-nitrobenzene | HCID 58241682 | — |
| Product | HCID 58241680 | HCID 58241680 | — |
Reaction Steps
1,3-Difluoro-2-iodo-4-nitrobenzene (5.0 g, 17.5 mmol) was dissolved in 50 ml of methanol, and NaOMe (3.79 g, 70.1 mmol) was added. The solution was heated under reflux for 16 h. After concentration, the residue was chromatographed on silica gel using petroleum ether/ethyl acetate. This gave 2-iodo-1,3-dimethoxy-4-nitrobenzene (3 g) as a yellowish powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08329619B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-acd36440914f4eba9771e3e77b553447 |
| Source note | uspto-grants-2012_12 |