Hydrazine hydrate (1:1) → 2-Chloro-3-hydrazinylpyrazine hydrochloride

Participants

Reaction Steps

A solution of 2,3-dichloropyrazine (3.822 g, 25.65 mmol) in absolute ethanol (20 mL) was treated with hydrazine hydrate (2.74 mL) at room temperature. The mixture was stirred for 3 days then filtered and washed with ethanol (20 mL) to yield 2-chloro-3-hydrazinylpyrazine hydrochloride as an off-white fluffy solid (4.04 g).

Provenance & Evidence