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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2191678Generated: November 2, 2026

Trifluoroacetic acid → HCID 57667999, compound

https://huagongshe.com/reaction/2191678

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantTert-butyl 2-(benzylamino)-4-phenethylbenzoateHCID 68961718—
ProductHCID 57667999HCID 5766799980.4%

Reaction Steps

Trifluoroacetic acid 2.0 mL was added to tert-butyl 2-(benzylamino)-4-phenethylbenzoate 0.16 g, it was stirred at room temperature 4 hours, and the solvent was removed under reduced pressure. Toluene was added to it, and the solvent was removed under reduced pressure. Diisopropyl ether and hexane were added to the obtained residue, solid matter was filtrated to give 2-(benzylamino)-4-phenethylbenzoic acid 0.11 g of white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08327467B2
Source datasetuspto-grants-2012_12
ORD IDord-edfd729b472742c287c9044e934bd238
Source noteuspto-grants-2012_12