Methanol → HCID 57667845, compound

Participants

Reaction Steps

2.0 mol/L Sodium hydroxide aqueous solution 0.92 mL was added to a mixed solution of methanol 2.0 mL and tetrahydrofuran 2.0 mL of methyl 2-(4-fluoroanilino)-4-(phenoxymethyl)benzoate 0.22 g, and it was stirred at room temperature for 24 hours. The solvent was removed under reduced pressure, water was added to it, and it was adjusted to pH4.0 with 1.0 mol/L hydrochloric acid. Solid matter was filtrated to give 2-(4-fluoroanilino)-4-(phenoxymethyl)benzoic acid 0.14 g of white solid.

Provenance & Evidence