Methanol → HCID 57668014, compound

Participants

Reaction Steps

To a mixed solution of methanol 4.0 mL and ethyl acetate 4.0 mL of 2-(4-fluoroanilino)-4-((E)-2-(4-(trifluoromethyl)phenyl)vinyl)benzoic acid 15 mg was added 5% palladium-carbon 8.0 mg at room temperature, and it was stirred under hydrogen atmosphere at room temperature for 10 hours. The solvent was removed under reduced pressure after insoluble matter was filtrated to give 2-(4-fluoroanilino)-4-(2-(4-(trifluoromethyl)phenyl)ethyl)benzoic acid 14 mg of white solid.

Provenance & Evidence