HCID 68960788, compound → HCID 57668052, compound

HRID 2191744Notes

Reaction equation

HRID 2191744 reaction equation
[CH3:1][O:2][C:3]1[CH:28]=[CH:27][C:6]([NH:7][C:8]2[CH:20]=[C:19]([C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)[CH:18]=[CH:17][C:9]=2[C:10]([O:12]C(C)(C)C)=[O:11])=[CH:5][CH:4]=1>FC(F)(F)C(O)=O>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([NH:7][C:8]2[CH:20]=[C:19]([C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)[CH:18]=[CH:17][C:9]=2[C:10]([OH:12])=[O:11])=[CH:27][CH:28]=1

Participants

3

Reactant 1

HCID 68960788HCID 68960788, compound

Product 1

HCID 57668052HCID 57668052, compound

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

Trifluoroacetic acid 10 mL was added to the obtained tert-butyl 2-(4-methoxyanilino)-4-phenylbenzoate, and it was stirred at room temperature for 2 hours. The solvent was removed under reduced pressure,diisopropyl ether was added to the obtained residue, and solid matter was filtrated to give 2-(4-methoxyanilino)-4-phenylbenzoic acid 44 mg of yellow solid.

Workup

  1. customThe solvent was removed under reduced pressure,diisopropyl ether
  2. additionwas added to the obtained residue, and solid matter
  3. filtrationwas filtrated

Sources & evidence

ORD record
ord-337f6c86efe04d808b28ffc3540be1bc
Source dataset
uspto-grants-2012_12
Patent number
US08327467B2

Reaction notes

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