HCID 68962795, compound → HCID 57667948, compound

HRID 2191750Notes

Reaction equation

HRID 2191750 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:27]=[CH:28][CH:29]=1)[NH:5][C:6]1[CH:18]=[C:17]([CH2:19][CH2:20][C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[CH:16]=[CH:15][C:7]=1[C:8]([O:10]C(C)(C)C)=[O:9]>FC(F)(F)C(O)=O>[Cl:1][C:2]1[CH:3]=[C:4]([CH:27]=[CH:28][CH:29]=1)[NH:5][C:6]1[CH:18]=[C:17]([CH2:19][CH2:20][C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=2)[CH:16]=[CH:15][C:7]=1[C:8]([OH:10])=[O:9]

Participants

3

Reactant 1

HCID 68962795HCID 68962795, compound

Product 1

HCID 57667948HCID 57667948, compound

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

Trifluoroacetic acid 10 mL was added to the obtained tert-butyl 2-(3-chloroanilino)-4-phenethylbenzoate, and it was stirred at room temperature for 2 hours. The solvent was removed under reduced pressure,diisopropyl ether was added to the obtained residue, and solid matter was filtrated to give 2-(3-chloroanilino)-4-phenethylbenzoic acid 21 mg of white solid.

Workup

  1. customThe solvent was removed under reduced pressure,diisopropyl ether
  2. additionwas added to the obtained residue, and solid matter
  3. filtrationwas filtrated

Sources & evidence

ORD record
ord-ba7a397aeec545c4b0b566380c75b6fe
Source dataset
uspto-grants-2012_12
Patent number
US08327467B2

Reaction notes

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