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HRID2191791

反应详情

EQUATION

反应方程式

HRID 2191791 的结构方程式

REACTANTS

反应物

1
结构：Cc1ccc(/C=C/c2ccc(C(=O)OC(C)(C)C)c(Nc3ccc(F)cc3)c2)cc1C
HCID68962926

未命名化合物

PRODUCTS

生成物

1
结构：Cc1ccc(/C=C/c2ccc(C(=O)O)c(Nc3ccc(F)cc3)c2)cc1C
HCID57668074

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：O=C(O)C(F)(F)F
溶剂HCID6422

未命名化合物

PROCEDURE

实验过程

Trifluoroacetic acid 10 mL solution of tert-butyl 4-((E)-2-(3,4-dimethylphenyl)vinyl)-2-(4-fluoroanilino)benzoate was stirred at room temperature for 2 hours. The solvent was removed under reduced pressure, and the obtained residue was refined by reversed-phase silica gel column chromatography [eluent; 85-100% acetonitrile/0.1% trifluoroacetic acid aqueous solution] to give 4-((E)-2-(3,4-dimethylphenyl)vinyl)-2-(4-fluoroanilino)benzoic acid.

WORKUP

后处理

  1. customThe solvent was removed under reduced pressure