Ethyl Acetate → HCID 57667895, compound

Participants

Reaction Steps

To the obtained 2-(4-fluoroanilino)-4-((E)-2-(4-(trifluoromethoxy)phenyl)vinyl)benzoic acid were added ethyl acetate 1.0 mL, methanol 1.0 mL and 10% palladium-carbon 2.0 mg sequentially, and it was stirred under hydrogen atmosphere at room temperature for 2 hours and 30 minutes. The solvent was removed under reduced pressure after insoluble matter was filtrated to give 2-(4-fluoroanilino)-4-(2-(4-(trifluoromethoxy)phenyl)ethyl)benzoic acid 3.4 mg of a white solid.

Provenance & Evidence