HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → 2-(4-Fluoroanilino)-4-(2-(2-methoxyphenyl)ethyl)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Tert-butyl 2-(4-fluoroanilino)-4-(2-(2-methoxyphenyl)ethyl)benzoate | HCID 68960995 | — |
| Product | 2-(4-Fluoroanilino)-4-(2-(2-methoxyphenyl)ethyl)benzoic acid | HCID 57668022 | 12.6% |
Reaction Steps
Trifluoroacetic acid 7.5 mL solution of tert-butyl 2-(4-fluoroanilino)-4-(2-(2-methoxyphenyl)ethyl)benzoate 0.11 g was stirred at room temperature for 2 hours. The solvent was removed under reduced pressure,diisopropyl ether was added to the obtained residue, and solid matter was filtrated to give 2-(4-fluoroanilino)-4-(2-(2-methoxyphenyl)ethyl)benzoic acid 12 mg of a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08327467B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-87f08c3a06e54d038df00d70960d2e9c |
| Source note | uspto-grants-2012_12 |