HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,6-Dichloropyrimidine → 3-bromo-1-(6-chloropyrimidin-4-yl)-6-(4-methoxyphenyl)-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,6-Dichloropyrimidine | HCID 70943 | — |
| Reactant | 3-bromo-6-(4-methoxyphenyl)-1H-indole | HCID 66955054 | — |
| Product | 3-bromo-1-(6-chloropyrimidin-4-yl)-6-(4-methoxyphenyl)-1H-indole | HCID 50991546 | — |
Reaction Steps
The target compound was prepared as in Example 9 using 3-bromo-6-(4-methoxyphenyl)-1H-indole (500 mg, 1.65 mmol) and 4,6-dichloropyrimidine (247 mg, 1.65 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08329708B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-427bb462aaae4ce8914d073ace23c6f1 |
| Source note | uspto-grants-2012_12 |