HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-4-methylpyridine → 2-Chloro-N-(4-methylpyridin-2-yl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-4-methylpyridine | HCID 1533 | — |
| Reactant | Chloroacetyl chloride | HCID 6577 | — |
| Product | 2-Chloro-N-(4-methylpyridin-2-yl)acetamide | HCID 2776797 | 74% |
Reaction Steps
The sub-titled compound (1.3 g, 74%, solid) was prepared by a similar procedure to that used to prepare Example 14f using 2-amino-4-methylpyridine in place of 2-amino-pyridine and adding the chloroacetyl chloride at room temperature rather than at 0° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08329729B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-4dc351a0bfee4dca8461d3430ce5058f |
| Source note | uspto-grants-2012_12 |