Ethyl 4-piperidinecarboxylate → HCID 58149897, compound

Participants

Reaction Steps

1-Chloro-5-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)isoquinoline (D7; 50 mg, 0.125 mmol), ethyl 4-piperidinecarboxylate (available from Fluorochem; 0.077 ml, 0.500 mmol) and n-butanol (0.75 ml) were heated under microwave irradiation at 175° C. for 2 h. The reaction mixture was filtered to give the title compound as an off white solid (35 mg).

Provenance & Evidence