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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2192473Generated: November 1, 2026

tert-Butyl piperazine-1-carboxylate → HCID 58149909, compound

https://huagongshe.com/reaction/2192473

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl piperazine-1-carboxylateHCID 143452—
ReactantHCID 58149900HCID 58149900—
Solvent1-ButanolHCID 263—
ProductHCID 58149909HCID 58149909—

Reaction Steps

1-Chloro-5-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)isoquinoline (D7; 50 mg), 1,1-dimethylethyl 1-piperazinecarboxylate (93 mg) and n-butanol (0.5 ml) were heated under microwave irradiation at 180° C. for 1 h. After cooling the reaction mixture was filtered and the title compound was isolated as a white solid (24 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08329730B2
Source datasetuspto-grants-2012_12
ORD IDord-870251a02f544563b5288a6a26c11ace
Source noteuspto-grants-2012_12