HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl piperazine-1-carboxylate → HCID 58149909, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl piperazine-1-carboxylate | HCID 143452 | — |
| Reactant | HCID 58149900 | HCID 58149900 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | HCID 58149909 | HCID 58149909 | — |
Reaction Steps
1-Chloro-5-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)isoquinoline (D7; 50 mg), 1,1-dimethylethyl 1-piperazinecarboxylate (93 mg) and n-butanol (0.5 ml) were heated under microwave irradiation at 180° C. for 1 h. After cooling the reaction mixture was filtered and the title compound was isolated as a white solid (24 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08329730B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-870251a02f544563b5288a6a26c11ace |
| Source note | uspto-grants-2012_12 |