反应详情

tert-Butyl (3S,5R)-3-[({2-tert-butyl-4-[(3-methoxypropyl)amino]pyrimidin-5-yl}carbonyl)(isobutyl)amino]-5-(morpholin-4-ylcarbonyl)piperidine-1-carboxylate (105 mg) is was dissolved in 1 M hydrogen chloride-ethyl acetate (6 ml), and the mixture was stirred at room temperature for 13 hr. The reaction mixture was concentrated to give the object compound (93 mg).

1. concentrationThe reaction mixture was concentrated