反应详情

tert-Butyl 3-[(acetyloxy)methyl]-5-{[(benzyloxy)carbonyl](2-methylpropyl)amino}piperidine-1-carboxylate (5.0 g) and palladium(II) hydroxide-carbon (500 mg) were suspended in methanol (100 ml), and the mixture was stirred under a hydrogen atmosphere (1 atm) at room temperature for 8 hr. The palladium catalyst was filtered off, and the filtrate was concentrated under reduced pressure to give the object compound (3.50 g).

1. filtrationThe palladium catalyst was filtered off
2. concentrationthe filtrate was concentrated under reduced pressure