HCID 59625453, compound → HCID 59625593, compound

Participants

Reaction Steps

tert-Butyl 3-[(acetyloxy)methyl]-5-{[(benzyloxy)carbonyl](2-methylpropyl)amino}piperidine-1-carboxylate (5.0 g) and palladium(II) hydroxide-carbon (500 mg) were suspended in methanol (100 ml), and the mixture was stirred under a hydrogen atmosphere (1 atm) at room temperature for 8 hr. The palladium catalyst was filtered off, and the filtrate was concentrated under reduced pressure to give the object compound (3.50 g).

Provenance & Evidence