反应详情

(3R,5S)-1-(tert-Butoxycarbonyl)-5-[({2-tert-butyl-4-[(3-methoxypropyl)amino]pyrimidin-5-yl}carbonyl)(isobutyl)amino]piperidine-3-carboxylic acid (102 mg) was dissolved in 1,4-dioxane (3 ml), water (100 μl) and 6 N hydrochloric acid (3 ml) were added and the mixture was stirred at room temperature for 3.5 hr. The reaction mixture was concentrated under reduced pressure to give the object compound (99 mg).

1. concentrationThe reaction mixture was concentrated under reduced pressure