反应详情

To a solution of 3-(iodomethyl)tetrahydrofuran (10.1 g) in acetonitrile (101 mL) was added triphenylphosphine (13.1 g), followed by heating under reflux for 1 week. The solution was concentrated under reduced pressure, followed by addition of diethyl ether. The resulting solid was collected by filtration and washed with diethyl ether to obtain triphenyl(tetrahydrofuran-3-ylmethyl)phosphonium iodide (18.8 g) as a white solid.

1. temperatureby heating
2. temperatureunder reflux for 1 week
3. concentrationThe solution was concentrated under reduced pressure
4. additionfollowed by addition of diethyl ether
5. filtrationThe resulting solid was collected by filtration
6. washwashed with diethyl ether