反应详情

0.38 g of 7-bromo-1-(1,3-dioxolan-2-ylmethyl)quinoxalin-2(1H)-one was dissolved in 15 mL of 80% aqueous trifluoroacetic acid solution, and stirred at room temperature for 16 hours. After the solvent was removed under reduced pressure, and the reaction mixture was alkalized by adding aqueous saturated sodium hydrogen carbonate solution, it was extracted with ethyl acetate. The organic layer was washed with aqueous saturated sodium chloride solution, dried over anhydrous magnesium sulfate, and the solvent was removed under reduced pressure to give (7-bromo-2-oxoquinoxalin-1(2H)-yl)acetaldehyde.

1. customAfter the solvent was removed under reduced pressure
2. additionby adding aqueous saturated sodium hydrogen carbonate solution, it
3. extractionwas extracted with ethyl acetate
4. washThe organic layer was washed with aqueous saturated sodium chloride solution
5. dry with materialdried over anhydrous magnesium sulfate
6. customthe solvent was removed under reduced pressure