HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoroaniline → 1-[(4-Fluorophenyl)carbamoyl]cyclopropanecarboxylic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoroaniline | HCID 9731 | — |
| Reactant | 1-(Phenylcarbamoyl)cyclopropanecarboxylic acid | HCID 19096871 | — |
| Product | 1-[(4-Fluorophenyl)carbamoyl]cyclopropanecarboxylic Acid | HCID 21081530 | 57% |
Reaction Steps
Following the procedure described above for the compound 161 (scheme 45), but replacing aniline for 4-fluoroaniline, title compound 181 was obtained in 57% yield. MS (m/z): 224.0 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08329726B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-10603b30188d4307aa5141635e72ac86 |
| Source note | uspto-grants-2012_12 |