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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2194019Generated: November 1, 2026

2-Thiophenesulfonyl chloride → HCID 49801070, compound

https://huagongshe.com/reaction/2194019

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Thiophenesulfonyl chlorideHCID 85518—
Reactant4-(Trifluoromethoxy)anilineHCID 600848—
Reactant4-(2-Methoxy-ethyl)-piperidine-4-carboxylic acid ethyl esterHCID 56753969—
ProductHCID 49801070HCID 49801070—

Reaction Steps

Light yellow solid. MS (ESI): 461.08 (MH+). This example was prepared in analogy to example 1 step C) to D) from 4-(2-methoxy-ethyl)-piperidine-4-carboxylic acid ethyl ester (example 1 step B)), thiophene-2-sulfonyl chloride and 4-(trifluoromethoxy)aniline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08329904B2
Source datasetuspto-grants-2012_12
ORD IDord-5c53331d58024f5b943f01f13da05a70
Source noteuspto-grants-2012_12