HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2,2-Trifluoro-1-(4-iodophenyl)ethanol → 8-(3,3-Dimethyl-butyryl)-2-[4-(2,2,2-trifluoro-1-hydroxy-ethyl)-phenyl]-2,8-diaza-spiro[4.5]decan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2,2-Trifluoro-1-(4-iodophenyl)ethanol | HCID 59440865 | — |
| Reactant | 8-(3,3-Dimethyl-butyryl)-2,8-diaza-spiro[4.5]decan-1-one | HCID 59578014 | — |
| Product | 8-(3,3-Dimethyl-butyryl)-2-[4-(2,2,2-trifluoro-1-hydroxy-ethyl)-phenyl]-2,8-diaza-spiro[4.5]decan-1-one | HCID 59577894 | — |
Reaction Steps
This material was prepared in analogy to example 148 step F) from 8-(3,3-dimethyl-butyryl)-2,8-diaza-spiro[4.5]decan-1-one and 2,2,2-trifluoro-1-(4-iodo-phenyl)-ethanol. Light yellow crystalline solid. MS (ESI): 427.3 MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08329904B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-7f1a0e3e309542eebea244c7f0416ca5 |
| Source note | uspto-grants-2012_12 |