HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2,2-Trifluoro-1-(4-iodophenyl)ethanol → 2-(4-(2,2,2-Trifluoro-1-hydroxyethyl)phenyl)-8-(2-(trifluoromethyl)phenylsulfonyl)-2,8-diazaspiro[4.5]decan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2,2-Trifluoro-1-(4-iodophenyl)ethanol | HCID 59440865 | — |
| Reactant | 8-(2-Trifluoromethyl-benzenesulfonyl)-2,8-diaza-spiro[4.5]decan-1-one | HCID 59577926 | — |
| Product | 2-(4-(2,2,2-Trifluoro-1-hydroxyethyl)phenyl)-8-(2-(trifluoromethyl)phenylsulfonyl)-2,8-diazaspiro[4.5]decan-1-one | HCID 59577944 | — |
Reaction Steps
This material was prepared in analogy to example 162 B) from 8-(2-trifluoromethyl-benzenesulfonyl)-2,8-diaza-spiro[4.5]decan-1-one and 2,2,2-trifluoro-1-(4-iodo-phenyl)-ethanol. White solid. MS (ESI): 537.12 MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08329904B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-69ed9138c12d43f49ad46f9ba35cc482 |
| Source note | uspto-grants-2012_12 |