HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2,2-Trifluoro-1-(4-iodophenyl)ethanol → 8-(Cyclopropylsulfonyl)-2-(4-(2,2,2-trifluoro-1-hydroxyethyl)phenyl)-2,8-diazaspiro[4.5]decan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2,2-Trifluoro-1-(4-iodophenyl)ethanol | HCID 59440865 | — |
| Reactant | 8-(Cyclopropylsulfonyl)-2,8-diazaspiro[4.5]decan-1-one | HCID 59577948 | — |
| Product | 8-(Cyclopropylsulfonyl)-2-(4-(2,2,2-trifluoro-1-hydroxyethyl)phenyl)-2,8-diazaspiro[4.5]decan-1-one | HCID 59577969 | — |
Reaction Steps
This material was prepared In analogy to example 162 step B) from 8-(cyclopropylsulfonyl)-2,8-diazaspiro[4.5]decan-1-one and 2,2,2-trifluoro-1-(4-iodo-phenyl)-ethanol. White solid. MS (ESI): 433.14 MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08329904B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-5edd8aebb23749858f83ed8af551d6b1 |
| Source note | uspto-grants-2012_12 |