HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Hydroxy-3-methylpentanoic acid → HCID 59577958, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Hydroxy-3-methylpentanoic acid | HCID 538288 | — |
| Reactant | O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate | HCID 2733207 | — |
| Reactant | 2-(4-Trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one acetic acid salt | HCID 66787333 | — |
| Product | HCID 59577958 | HCID 59577958 | — |
Reaction Steps
The title compound was prepared in analogy to example 13 step A (using TBTU instead of BOP as the coupling reagent) from 2-(4-trifluoromethoxy-phenyl)-2,8-diaza-spiro[4.5]decan-1-one acetic acid salt (described in example 180 step C) and 3-hydroxy-3-methyl-pentanoic acid. Light brown oil. MS (ESI): 429.2 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08329904B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-b7c2043098a546c08a5791def872e36f |
| Source note | uspto-grants-2012_12 |