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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2194206Generated: October 31, 2026

5-Bromo-2,2-difluoro-1,3-benzodioxole → HCID 59578084, compound

https://huagongshe.com/reaction/2194206

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-2,2-difluoro-1,3-benzodioxoleHCID 2736271—
Reactant8-(2-Chloro-benzenesulfonyl)-2,8-diaza-spiro[4.5]decan-1-oneHCID 59577994—
ProductHCID 59578084HCID 59578084—

Reaction Steps

The title compound was prepared in analogy to example 148 step F) from 8-(2-chloro-benzenesulfonyl)-2,8-diaza-spiro[4.5]decan-1-one (described in example 148 step E or example 179 step A for an alternative synthesis) and 5-bromo-2,2-difluoro-benzo[1,3]dioxole. Off-white solid. MS (ESI): 485.1 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08329904B2
Source datasetuspto-grants-2012_12
ORD IDord-722016cb51fa45088a682831a6627cb5
Source noteuspto-grants-2012_12