Sodium Hydroxide → HCID 59571714, compound

Participants

Reaction Steps

0.5 N sodium hydroxide solution (3.1 mL) was added to the solution of 980 mg of (+)-2-{9-[3-methoxy-4-((5-methyl-2-phenyl-oxazole-4-yl)methoxy)-benzyl]-9H-carbazole-4-yloxy}-2-phenylacetic acid in 2-propanol (30 mL). 2-propanol was removed under reduced pressure, the residue was collected by filtration with a small amount of 2-propanol, and 850 mg of the subject compound was prepared as pale brown powder. Optical purity>99% ee (HPLC)

Provenance & Evidence