HCID 11714078, compound → HCID 59571734, compound

Participants

Reaction Steps

Sodium 2-ethylhexanoate (479 mg) was added to the solution of 1.5 g of 4-{9-[3-methoxy-4-((5-methyl-2-phenyl-oxazole-4-yl)methoxy)-benzyl]-9H-carbazole-4-yloxy}-2-methyl-butyric acid prepared by the example 52(b) in ethyl acetate (15 mL) at room temperature. After stirring at room temperature for 30 minutes, the precipitate was isolated by filtration, washed with ethanol, dried under reduced pressure, and 1.49 g of the subject compound was prepared as white powder. Optical purity>99% ee (HPLC)

Provenance & Evidence