HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → 4-(2-Methyl-4-m-tolylethynyl-imidazol-1-yl)-1H-pyridin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 2-Chloro-4-(2-methyl-4-m-tolylethynyl-imidazol-1-yl)-pyridine | HCID 86649881 | — |
| Solvent | tert-Butanol | HCID 6386 | — |
| Product | 4-(2-Methyl-4-m-tolylethynyl-imidazol-1-yl)-1H-pyridin-2-one | HCID 49872672 | — |
Reaction Steps
The title compound, white solid, MS: m/e=290.1 (M+H+), was prepared in accordance with the general method of example 1a from 2-chloro-4-(2-methyl-4-m-tolylethynyl-imidazol-1-yl)-pyridine and KOH in tert-butanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08334287B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-67c74baabb46448990a40917cc4f0f0f |
| Source note | uspto-grants-2012_12 |