Iodoethane → 1-Ethyl-4-(2-methyl-4-m-tolylethynyl-imidazol-1-yl)-1H-pyridin-2-one
Reaction equation
[CH3:1][C:2]1[N:3]([C:16]2[CH:21]=[CH:20][NH:19][C:18](=[O:22])[CH:17]=2)[CH:4]=[C:5]([C:7]#[C:8][C:9]2[CH:10]=[C:11]([CH3:15])[CH:12]=[CH:13][CH:14]=2)[N:6]=1.[CH2:23](I)[CH3:24]>>[CH2:23]([N:19]1[CH:20]=[CH:21][C:16]([N:3]2[CH:4]=[C:5]([C:7]#[C:8][C:9]3[CH:10]=[C:11]([CH3:15])[CH:12]=[CH:13][CH:14]=3)[N:6]=[C:2]2[CH3:1])=[CH:17][C:18]1=[O:22])[CH3:24]Participants
3
Procedure
The title compound, light brown solid, MS: m/e=318.2 (M+H+), was prepared in accordance with the general method of example 3 from 4-(2-Methyl-4-m-tolylethynyl-imidazol-1-yl)-1H-pyridin-2-one and ethyl iodide.
Sources & evidence
- ORD record
- ord-432e9cc1b19c4dc1a98553c5030b67cd
- Source dataset
- uspto-grants-2012_12
- Patent number
- US08334287B2
Reaction notes
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