Methyl iodide → HCID 58111185, compound

Participants

Reaction Steps

The title compound, yellow cristalline solid, MS: m/e=326.1, 328.2 (M+H+), was prepared in accordance with the general method of example 3 from 6-[4-(2-chloro-pyridin-4-ylethynyl)-2-methyl-imidazol-1-yl]-1H-pyrazin-2-one and methyl iodide, along with the O-alkylation product from which it was separated by flash chromatography (gradient: EtOAc to EtOAc/MeOH 95:5).

Provenance & Evidence