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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2194427Generated: November 1, 2026

2-Bromoethyl methyl ether → 4-[4-(3-chloro-phenylethynyl)-2,5-dimethyl-imidazol-1-yl]-1-(2-methoxy-ethyl)-1H-pyridin-2-one

https://huagongshe.com/reaction/2194427

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromoethyl methyl etherHCID 80972—
Reactant4-[4-(3-chloro-phenylethynyl)-2,5-dimethyl-imidazol-1-yl]-1H-pyridin-2-oneHCID 49872578—
Product4-[4-(3-chloro-phenylethynyl)-2,5-dimethyl-imidazol-1-yl]-1-(2-methoxy-ethyl)-1H-pyridin-2-oneHCID 49872670—

Reaction Steps

The title compound, white crystalline solid, MS: m/e=382.3, 384.1 (M+H+), was prepared in accordance with the general method of example 3 from 4-[4-(3-chloro-phenylethynyl)-2,5-dimethyl-imidazol-1-yl]-1H-pyridin-2-one and 2-bromoethyl-methylether.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08334287B2
Source datasetuspto-grants-2012_12
ORD IDord-d80d3cfd1a534c4ebd249cbd10c65569
Source noteuspto-grants-2012_12