Iodoethane → 4-[2,5-dimethyl-4-m-tolylethynyl-imidazol-1-yl]-1-ethyl-1H-pyridin-2-one

HRID 2194430Notes

Reaction equation

HRID 2194430 reaction equation
[CH3:1][C:2]1[N:3]([C:17]2[CH:22]=[CH:21][NH:20][C:19](=[O:23])[CH:18]=2)[C:4]([CH3:16])=[C:5]([C:7]#[C:8][C:9]2[CH:10]=[C:11]([CH3:15])[CH:12]=[CH:13][CH:14]=2)[N:6]=1.[CH2:24](I)[CH3:25]>>[CH3:1][C:2]1[N:3]([C:17]2[CH:22]=[CH:21][N:20]([CH2:24][CH3:25])[C:19](=[O:23])[CH:18]=2)[C:4]([CH3:16])=[C:5]([C:7]#[C:8][C:9]2[CH:10]=[C:11]([CH3:15])[CH:12]=[CH:13][CH:14]=2)[N:6]=1

Participants

3

Reactant 2

HCID 6340IodoethaneHCID 581111894-(2,5-dimethyl-4-m-tolylethynyl-imidazol-1-yl)-1H-pyridin-2-one

Product 1

HCID 498727654-[2,5-dimethyl-4-m-tolylethynyl-imidazol-1-yl]-1-ethyl-1H-pyridin-2-one

Procedure

The title compound, light brown solid, MS: m/e=332.2 (M+H+), was prepared in accordance with the general method of example 3 from 4-[2,5-dimethyl-4-m-tolylethynyl-imidazol-1-yl]-1H-pyridin-2-one and ethyl iodide.

Sources & evidence

ORD record
ord-2b578f28f6474663baa0f301d47aff2e
Source dataset
uspto-grants-2012_12
Patent number
US08334287B2

Reaction notes

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