HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodoethanol → 4-[4-(2-chloro-pyridin-4-ylethynyl)-2,5-dimethyl-imidazol-1-yl]-1-(2-hydroxy-ethyl)-1H-pyridin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodoethanol | HCID 12225 | — |
| Reactant | 4-[4-(2-chloro-pyridin-4-ylethynyl)-2,5-dimethyl-imidazol-1-yl]-1H-pyridin-2-one | HCID 58111187 | — |
| Product | 4-[4-(2-chloro-pyridin-4-ylethynyl)-2,5-dimethyl-imidazol-1-yl]-1-(2-hydroxy-ethyl)-1H-pyridin-2-one | HCID 58111188 | — |
Reaction Steps
The title compound, orange solid, MS: m/e=369.0, 371.2 (M+H+), was prepared in accordance with the general method of example 3 from 4-[4-(2-chloro-pyridin-4-ylethynyl)-2,5-dimethyl-imidazol-1-yl]-1H-pyridin-2-one and 2-iodoethanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08334287B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-0a85499b99a3468494e9d728587ae5be |
| Source note | uspto-grants-2012_12 |