化工社化工社 化学情報印刷レポート · 研究参考用
Potassium Hydroxide → 6-(4-iodo-2,5-dimethyl-imidazol-1-yl)-3H-pyrimidin-4-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Hydroxide | HCID 14797 | — |
| 反応物 | 4-Fluoro-6-(4-iodo-2,5-dimethyl-imidazol-1-yl)-pyrimidine | HCID 66865373 | — |
| 溶媒 | tert-Butanol | HCID 6386 | — |
| 生成物 | 6-(4-iodo-2,5-dimethyl-imidazol-1-yl)-3H-pyrimidin-4-one | HCID 136395152 | — |
反応手順
The title compound, light yellow crystalline solid, MS: m/e=316.9 (M+H+), was prepared in accordance with the general method of example 1a by treatment of 4-fluoro-6-(4-iodo-2,5-dimethyl-imidazol-1-yl)-pyrimidine with 50% KOH in tert-butanol.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08334287B2 |
| 出典データセット | uspto-grants-2012_12 |
| ORD ID | ord-5df26ff679614090a43961b87df68ba8 |
| 出典メモ | uspto-grants-2012_12 |