HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-3-ethynylbenzene → 5-[4-(3-Chloro-phenylethynyl)-2-methyl-imidazol-1-yl]-2-(2-m ethoxy-ethyl)-2H-pyridazin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-3-ethynylbenzene | HCID 123086 | — |
| Reactant | 2-(2-methoxy-ethyl)-5-(4-iodo-2-methyl-imidazol-1-yl)-2H-pyridazin-3-one | HCID 66865128 | — |
| Product | 5-[4-(3-Chloro-phenylethynyl)-2-methyl-imidazol-1-yl]-2-(2-m ethoxy-ethyl)-2H-pyridazin-3-one | HCID 49872770 | — |
Reaction Steps
The title compound, yellow crystalline solid, MS: m/e=369.2, 370.9 (M+H+), was prepared in accordance with the general method of example 21a from 5-(4-Iodo-2-methyl-imidazol-1-yl)-2-(2-methoxy-ethyl)-2H-pyridazin-3-one and 1-chloro-3-ethynyl-benzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08334287B2 |
| Source dataset | uspto-grants-2012_12 |
| ORD ID | ord-89b040572f0f4694ba9e4054aea0d75f |
| Source note | uspto-grants-2012_12 |